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Labs / Hyde Park, Chicago
Hyde Park Labs
Home of the UChicago Science Incubator.
5207 S. Harper Ave, Suite 500
Explore our spaces
You can
build here.
The UChicago Science Incubator enables early-stage science and technology startups to translate ideas into commercial opportunities.
Book a tourHyde Park Labs sits where the Checkerboard Lounge once stood. The Checkerboard was the South Side blues club founded by Buddy Guy and L.C. Thurman, and it played Harper Court until 2015. It was a room where people came to make something new, together and late into the night. We carried that forward: our space is filled with records from Chicago’s legends across blues, soul, jazz and beyond, a nod to the city’s long habit of turning shared rooms into something new.
Explore this site’s spaces and amenities below. Connect with the local team to discuss membership, equipment, and the support your company needs.
Located in Hyde Park Labs
22,000 sq. ft.
Shared equipment and amenities
Four focus areas
Side A
The UChicago Science Incubator gives early-stage life sciences, quantum, clean energy and data science companies access to state-of-the-art facilities and amenities, cutting-edge wet lab space and equipment, and the seasoned management expertise they need to flourish.
Life sciences
Quantum
Clean energy
Data science
We will enhance your lab workflow with our state-of-the-art equipment or procure custom solutions based on your needs.
Located in Hyde Park Labs, a 300,000+ square-foot facility near the University of Chicago’s main campus and medical center.
5207 S. Harper Ave, Suite 500, Chicago, IL 60615
The Incubator is a space for startups, researchers and industry experts to work together, powered by Portal and the University of Chicago’s Polsky Center.
Members also get Portal Pass access to work at Portal sites in Fulton Market, Providence and New Brunswick.
- University of Chicago
- Polsky Center
For direct inquiries, email Raul Vasquez, Executive Director of the UChicago Science Incubator.
ADDRESS
5207 S. Harper Ave, Suite 500, Chicago, IL 60615
Let’s build what’s next.
© 2026 Portal Innovations LLC
Capital. Space. Expertise.
